The treatment of VUR is now mostly conservative. However in Grade 3 sometimes and 4 and 5 most of the time, surgery is needed. To prevent surgery the use of bulking agents were used. But these were toxic, tended to migrate or disappear altogether.
DEFLUX is made of two types of sugar-based molecules (polysaccharides) called dextranomer and hyaluronic acid. Both substances are well-known from previous uses in medicine. Both materials are also biocompatible, which means that they do not cause significant reactions within the body. In fact, hyaluronic acid is produced and found naturally within the body.
Therefore if this has some long-standing support, stays in and prevents VUR that is, it could be a useful adjunct in the therapeutic armamentorium..
The cost is the other factor to be considered, of course.
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